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35 Episodes
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Dr. Jason Tresser explains the controlling factors of gene expression in a bacterial cell. He describes the regions of genetic code that activate or repress a gene and how these function in response to stimuli.
Dr. Jason Tresser explains the processes of spermatogenesis and oogenesis during which gamete cells are produced. He discusses sex-linked traits and the processes that determine sex in an organism.
Dr. Jason Tresser discusses sex determination in various species. He covers the primary mechanisms that determine sex and some of the deviations that can occur, particularly in humans.
Dr. Jason Tresser explains how to construct a genetic library. He goes on to discuss a number of methods that can be used to sequence DNA, showing how modern techniques have continued to improve upon the techniques used in the past.
Dr. Jason Tresser explains non-Mendelian genetics and the various factors that can cause changes in inheritance ratios. He goes on to explain how certain phenotypes can be suppressed by factors outside the genome itself.
Dr. Jason Tresser explains the various types of mutations that can occur in an organism's genetic material. He explains how mutations can be chemically induced as well as how they can appear naturally in a cell.
Dr. Jason Tresser explains the process of cloning a specific bacterial gene and the function of restriction enzymes. He goes on to discuss how restriction enzymes can be used to construct a map of a strand of DNA.
Dr. Jason Tresser explains the next-generation processes used to sequence DNA: pyrosequencing and SOLiD sequencing. He then explains genotyping, a process of identifying known alleles in an individual's genome.
Dr. Jason Tresser concludes his teaching on genotyping and goes on to discuss transgenics. He explains the necessary components of a gene that must be in place for a host cell to utilize a foreign segment of DNA.
Dr. Jason Tresser explains how transgenics can be used to identity the expression of particular genes in an organism. He describes how genes can be probed to identify the mRNA being expressed in a cell and how this process can be used in microarrays.
Dr. Jason Tresser explains how gene expression is regulated in a cell beyond the DNA phase. He explains how various types of RNA can interact with and edit one another, as well as how a protein can be regulated even after it has been created.
Dr. Jason Tresser explains the developmental processes of embryos as they differentiate into various types of cells. He explains the general mechanisms that surround this process and how the process can be tracked.
Dr. Jason Tresser explains the origin and behavior of cancer cells. He describes the various ways that these cells can be identified and some of the ways that they can be treated.
Dr. Jason Tresser describes how alleles can be tracked in a population. He explains the Hardy-Weinberg Law, which outlines the conditions for genetic stasis, and the ways genes are commonly seen to move through a population.
Dr. Jason Tresser explains how genes can be compared between members of the same species or between similar species. This process can be used to track where genes have changed over time, and can be used to roughly estimate the common ancestry of related species.
Dr. Jason Tresser explains how the manifestation of a genotype can be altered by the way a cell manages its gene expression. He goes on to explain linkage, where genes share a chromosome, and how these genes can be affected by recombination.
Dr. Jason Tresser discusses with his class the ethical issues raised by embryonic research. He argues for the sanctity of life and presents several unique alternatives to the commonly presented options of abortion.
Dr. Jason Tresser explains various processes for cloning segments of genetic code. He considers a number of bacterial methods of cloning and notes that yeast can be used as well. Dr. Tresser concludes with a brief explanation of genomic libraries.
Dr. Jason Tresser explains how the expression of genes is controlled in multicellular organisms. He describes the various types of proteins that act as activators and repressors in a cell.
Dr. Jason Tresser describes several processes of transferring DNA between bacteria. He explains how phages infect bacteria with their own DNA and how this process can be manipulated to intentionally append bacterial genomes.
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